The laboratory of Dr. David Riches, Program in Cell Biology, Department of Pediatrics at National Jewish Health is seeking to recruit a highly motivated Postdoctoral Research Associate to work on a project focused on lung injury, repair and fibrosis in. Our laboratory has longstanding interests in determining how lung injury leads to detrimental lung fibrosis, especially persistent and progressive lung disease, as seen in the human lung disease, idiopathic pulmonary fibrosis.
The successful applicant will join a new project focused on investigating the mechanisms linking mis-expression of the mucin MUC5B in the distal lung and terminal bronchioles to fibroblast accumulation and activation in the context of persistent lung fibrosis. Most of the experimental work will be with a mouse model of lung fibrosis, with translational studies being conducted using primary human lung cells and tissues. The project will require a strong background in mouse breeding, multi-parameter flow cytometry, preparation of tissues and pathophysiologic assessments of lung disease, and basic laboratory skills including cell culture, RNA isolation, Western blotting and fluorescence microscopy. A basic understanding of bioinformatic approaches to analyze big RNA-sequencing data sets is desirable.
Post-doctoral Associates in our lab are offered opportunities for academic career advancement through mentorship, writing, attending workshops, by presenting their work at national meetings and by seeking extramural funding. Successful applicants will have a Ph.D. or equivalent degree in a relevant field, and quality publications in peer-reviewed journal.
To perform, on a very independent basis, all phases of experimental investigations and to collaborate with Principal Investigators and senior researchers in the progress of major research projects. To act as technical advisor to laboratory technical, support and auxiliary staff.
- Performs, on a very independent basis, all phases of experimental investigations, to include being responsible to the Principal Investigator in the planning, developing, operating, recording, collaborating and reporting of major projects.
- Collaborates with Principal Investigators and senior researchers in the progress of major research projects.
- Provides guidance to laboratory staff in one or more laboratory areas, including technicians, support and auxiliary staff. Performs as the technical advisor on techniques involving complex analyses utilizing highly sophisticated techniques. Serves as primary contact with researcher staff for technical services on major techniques, recording devices and statistical procedures relative to the specifically assigned field.
- Reviews quality control of new or modified laboratory techniques which affect any part of major projects.
- Performs routine and non-routine tests leading to the successful completion of developed experiments. Knows and follows age-specific guidelines.
- Performs as a back-up to staff absences and vacancies, as necessary.
- Accountability: Accepts full responsibility for self and contribution as a team member; displays honesty and truthfulness; confronts problems quickly; displays a strong commitment to organizational success and inspires others to commit to goals; demonstrates a commitment to National Jewish Health.
- Laboratory Knowledge: Demonstrates and understands laboratory testing and methodology.
- Decision Quality: Makes good decisions based upon a mixture of analysis, wisdom, experience, and judgement. Sought out by others for advice and solutions.
- Adaptability: Maintains effectiveness in the midst of change in work responsibilities or environment, requirements ambiguity, or stress.
- Problem Solving: Uses issue identification, data relation and comparison, pattern recognition and information gathering to create analyses and make recommendations.
- Informing/Communicating: Conveys ideas, responses, or instructions effectively, appropriately, and persuasively through writing or speech.
- Professional Relationships: Interacts with others in a constructive, positive, and respectful manner, regardless of individual differences. Assists team members or co-workers in achieving personal goals and completing assignments.
- Drive for Excellence: Consistently meets performance expectations, ensures that accurate, objective, and timely measures of quality are made and used.
- Innovation Management: Identifies key trends, opportunities, and organizational capabilities that would bring competitive advantage to the organization. Sees trends before others and integrates concepts in a unique way.
Supervisory or Managerial Responsibility
- Be available to work as scheduled and report to work on time.
- Be willing to accept supervision and work well with others.
- Be well groomed, appropriately for your role and wear ID Badge visibly.
- Be in compliance with all departmental and institutional policies, the Employee Handbook, Code of Conduct and completes NetLearning by due date annually.
- Fosters an inclusive workplace where diversity and individual differences are valued and leveraged to achieve the vision and mission of the institution.
- Adheres to safe working practices and at all times follows all institutional and departmental safety policies and procedures.
- Wears appropriate PPE as outlined by the infection control policies and procedures.
- Demonstrates compliance with all state, federal and all other regulatory agency requirements.
- Education: MD or PhD in biology, chemistry or other basic sciences required.
- Work Experience: A minimum of five years of specified experience in technical investigatory techniques required. MD or PhD in a specified basic science field will suffice for 2 years experience.
- Special Training, Certification or Licensure: None
Salary Range: $55,000 - $65,000
At National Jewish Health, we recognize that our outstanding faculty and staff are the essence of our organization. For every aspect of health care, our employees are our greatest asset.
With that in mind, we have designed a valuable, comprehensive benefits package to meet the needs of our employees and their families.
- Medical Plans, Dental Plans and Vision Insurance
- Retirement Plan
- FSA and HSA
- Short and Long Term Disability
- Life Insurance and AD&D
- Voluntary Benefits, like Accident Insurance, Critical Care and Hospital Indemnity
- Sick and Vacation Paid Time Off
- Wellness Program
- Legal Plan