Senior Lab Researcher - Mouse Genetics

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  • Denver, CO
  • *National Jewish Health - Main Campus
  • Mouse Genetics
  • Full Time - Day Shift
  • Laboratory Research
  • Req #: 16919
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Position Summary    

This position plays a central role in the Mouse Genetics Core breeding program. Leads work necessary to establish germline transmission and maintain independent mouse lines in a timely fashion, including but not limited to ensuring the integrity of the genetic modifications in individual animals by sequencing and transferring and/or cryopreserving models as appropriate to meet the needs of the researcher.   

Essential Duties    

  1. Organizes and implements complex breeding colony management through timed matings, careful handling of animals for mouse identification, health monitoring and weaning. Performs genotyping as needed to facilitate colony management decisions. 
  2. Facilitates the generation of novel mouse models, including setting up and generating pseudo pregnant females, superovulation, mating, and harvest of embryos, potentially microinjection or electroporation of embryos, and embryo transfer surgeries. 
  3. Updates weekly census reports and orders mice to replenish the colony, as needed. 
  4. Serves as an accessible and responsive technical resource for both investigators and their laboratory staff. This includes timely updates on projects in progress and support during the live animal import/export process. 
  5. Performs technical research on assigned experiments through the use of self-generated and cooperatively developed investigative methodologies that are based on knowledge of the field, relevant literature and analysis of available data.  
  6. Collects, accurately records, analyzes and shares data in conjunction with other research staff such as genotyping and sequencing. Reviews, develops and implements quality control of new or modified laboratory techniques that may affect any part of major projects. 
  7. Replenishes inventory as needed, reports issues with equipment use and maintenance for the micro injection laboratory and mouse colonies as needed. 
  8. Compiles and submits all chargebacks for facility revenue in a timely manner. Ensures the accuracy of invoices that have been submitted. 
  9. Maintains laboratory records, supplies, and samples in an organized manner, such as laboratory notebooks and gDNA samples used for genotyping.  
  10. Ensures laboratory and staff are compliant with departmental, center, and regulatory policies.

Other Duties

Performs as a back-up to staff absences and vacancies, as necessary.


  1. Accountability: Accepts full responsibility for self and contribution as a team member; displays honesty and truthfulness; confronts problems quickly; displays a strong commitment to organizational success and inspires others to commit to goals; demonstrates a commitment to National Jewish Health. 
  2. Laboratory Knowledge: Demonstrates and understands laboratory testing and methodology.
  3. Decision Quality: Makes good decisions based upon a mixture of analysis, wisdom, experience, and judgement.   Sought out by others for advice and solutions.
  4. Adaptability: Maintains effectiveness in the midst of change in work responsibilities or environment, requirements ambiguity, or stress.
  5. Problem Solving: Uses issue identification, data relation and comparison, pattern recognition and information gathering to create analyses and make recommendations.
  6. Informing/Communicating: Conveys ideas, responses, or instructions effectively, appropriately, and persuasively through writing or speech.
  7. Collaboration/Teamwork: Cooperates with others to accomplish common goals; works with principal investigators and members of their laboratories as well as other core facility colleagues to achieve shared goals.  Treats others with dignity and respect and maintains a friendly demeanor; values the contributions of others. 
  8. Drive for Excellence: Consistently meets performance expectations, ensures that accurate, objective, and timely measures of quality are made and used.
  9. Attention to Detail: Accomplishing tasks by considering all areas involved, no matter how small; showing concern for all aspects of the job; accurately checking processes and tasks; being watchful over a period of time. Setting high standards of performance for self and others; assuming responsibility and accountability for successfully completing assignments or tasks; self-imposing standards of excellence rather than having standards imposed.

Supervisory or Managerial Responsibility    






Core Values    

  1. Be available to work as scheduled and report to work on time.
  2. Be willing to accept supervision and work well with others.
  3. Be well groomed, appropriately for your role and wear ID Badge visibly.
  4. Be in compliance with all departmental and institutional policies, the Employee Handbook, Code of Conduct and completes NetLearning by due date annually.
  5. Fosters an inclusive workplace where diversity and individual differences are valued and leveraged to achieve the vision and mission of the institution.
  6. Adheres to safe working practices and at all times follows all institutional and departmental safety policies and procedures. 
  7. Wears appropriate PPE as outlined by the infection control policies and procedures.
  8. Demonstrates compliance with all state, federal and all other regulatory agency requirements.

Minimum Qualifications

Education: BS/BA degree required. 
Work Experience: 5 years of laboratory experience required. A Master’s degree and 3 years of laboratory experience may be substituted for the required 5 years of work experience. Expertise in animal husbandry and molecular biology preferred. 
Special Training, Certification or Licensure: None


Salary Range: $55,000 - $65,000



At National Jewish Health, we recognize that our outstanding faculty and staff are the essence of our organization. For every aspect of health care, our employees are our greatest asset.

With that in mind, we have designed a valuable, comprehensive benefits package to meet the needs of our employees and their families.

  • Medical Plans, Dental Plans and Vision Insurance
  • Retirement Plan
  • FSA and HSA
  • Short and Long Term Disability
  • Life Insurance and AD&D
  • Voluntary Benefits, like Accident Insurance, Critical Care and Hospital Indemnity
  • Sick and Vacation Paid Time Off
  • Wellness Program
  • Legal Plan



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